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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
19.7
Human Site:
S749
Identified Species:
36.11
UniProt:
P39880
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39880
NP_853530.2
1505
164273
S749
T
P
K
L
L
S
T
S
P
M
P
T
V
S
S
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
S760
T
P
K
L
L
S
T
S
P
M
P
T
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
S1026
T
P
K
L
L
S
T
S
P
M
P
T
V
S
S
Dog
Lupus familis
XP_546939
1411
154543
Q725
A
I
R
S
I
L
Q
Q
A
R
R
E
M
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P53564
1515
165577
S747
T
P
K
H
L
S
A
S
P
M
S
T
V
S
T
Rat
Rattus norvegicus
P53565
862
92341
R205
K
T
G
S
S
Q
P
R
A
E
R
S
Q
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
Y785
S
Q
N
I
V
Q
A
Y
I
K
Q
E
E
G
P
Chicken
Gallus gallus
XP_425393
1673
183755
S894
S
P
K
L
V
S
T
S
A
M
S
S
V
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
E686
P
P
F
I
K
Q
E
E
G
I
S
V
P
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
P1110
F
P
S
F
L
F
S
P
S
L
F
G
G
A
A
Honey Bee
Apis mellifera
XP_623857
1936
209316
T1074
F
T
H
F
F
S
G
T
Q
E
D
F
R
L
A
Nematode Worm
Caenorhab. elegans
Q9BL02
1273
143507
Y616
C
K
R
L
M
I
A
Y
N
I
G
Q
R
L
F
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
N771
R
E
P
P
T
P
P
N
L
N
G
D
I
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
83.1
56.2
N.A.
88.8
47.1
N.A.
44.3
77.4
N.A.
40.9
N.A.
23.3
23.7
22.3
29.1
Protein Similarity:
100
98.6
83.4
64.5
N.A.
91.8
50
N.A.
60
81.7
N.A.
55.4
N.A.
37.4
41
41
46.6
P-Site Identity:
100
100
100
0
N.A.
73.3
0
N.A.
0
66.6
N.A.
13.3
N.A.
13.3
6.6
6.6
0
P-Site Similarity:
100
100
100
26.6
N.A.
80
6.6
N.A.
20
86.6
N.A.
26.6
N.A.
40
20
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
24
0
24
0
0
0
0
16
24
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
0
8
0
0
0
0
8
8
0
16
0
16
8
8
0
% E
% Phe:
16
0
8
16
8
8
0
0
0
0
8
8
0
0
8
% F
% Gly:
0
0
8
0
0
0
8
0
8
0
16
8
8
8
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
16
8
8
0
0
8
16
0
0
8
0
0
% I
% Lys:
8
8
39
0
8
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
39
39
8
0
0
8
8
0
0
0
24
0
% L
% Met:
0
0
0
0
8
0
0
0
0
39
0
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
8
8
8
0
0
0
0
0
% N
% Pro:
8
54
8
8
0
8
16
8
31
0
24
0
8
0
8
% P
% Gln:
0
8
0
0
0
24
8
8
8
0
8
8
8
8
8
% Q
% Arg:
8
0
16
0
0
0
0
8
0
8
16
0
16
0
8
% R
% Ser:
16
0
8
16
8
47
8
39
8
0
24
16
0
39
39
% S
% Thr:
31
16
0
0
8
0
31
8
0
0
0
31
0
0
8
% T
% Val:
0
0
0
0
16
0
0
0
0
0
0
8
39
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _